Fall 2013      MATH:7450 (22M:305) Topics in Topology: Scientific and Engineering Applications of Algebraic Topology

Instructor:  Dr. Isabel K. Darcy
Email: idarcybiomath AT gmail.com

Live lectures are held MWF 16:30 - 17:20 GMT (11:30am - 12:20pm CDT, Iowa time).

To join a live lecture, e-mail me (idarcybiomath AT gmail.com) for the URL.

The live lectures are recorded and posted on youtube. See links below or my youtube page. Powerpoint slides (also in pdf) are also available below.

     Preparatory videos introducing algebraic topology are available here.

     The links below include both recommended as well as supplementary reading for those who wish to go deeper into a subject. Recommended vs supplementary reading will be distinguished at a later date.

Tentative Schedule:

Week 1 Topological Data Analysis: Software Mapper
Aug 26 video, pptx, pdf Extracting insights from the shape of complex data using topology P. Y. Lum, G. Singh, A. Lehman, T. Ishkanov, M. Vejdemo-Johansson, M. Alagappan, J. Carlsson, G. Carlsson (2013)
Aug 28 video, pptx, pdf Topology based data analysis identifies a subgroup of breast cancers with a unique mutational profile and excellent survival M. Nicolau, A. J. Levine, G. Carlsson (2011)
Aug 30 video, pptx, pdf Download Mapper for Matlab
Python Mapper
Graphviz
Web tool: Progression Analysis of Disease - PAD (includes Mapper)
Ayasdi Iris, academic trial
Additional readings:
Topological Methods for the Analysis of High Dimensional Data Sets and 3D Object Recognition G. Singh , F. Memoli, G. Carlsson (2007)
Topology and data, G Carlsson (2009) (Mapper: p. 281 - 289)
DNA MICROARRAY VIRTUAL LAB, youtube video
How to Analyze DNA Microarray Data, Howard Hughes Medical Institute
Pearson Product-Moment Correlation
Week 2 Homology
Sept 2 Holiday: No class
Sept 4 video, pptx, pdf Section 2 in H. Edelsbrunner, D. Letscher, and A. Zomorodian, Topological persistence and simpliction, Discrete and Computational Geometry 28, 2002, 511-533.
Discriminative persistent homology of brain networks, Hyekyoung Lee; Chung, M.K.; Hyejin Kang; Bung-Nyun Kim; Dong Soo Lee, Biomedical Imaging: From Nano to Macro, 2011 IEEE International Symposium on , vol., no., pp.841,844, March 30 2011-April 2 2011.
Sept 6 video, pptx, pdf A. Zomorodian and G. Carlsson , Computing persistent homology, Discrete and Computational Geometry, 33 (2), pp. 247-274. Jan 2005
4.1 - 4.3 in Herbert Edelsbrunner and John L. Harer, Computational Topology, American Mathematical Society (December 8, 2009) google books preview
Ch 4 and sect 7.3.1 in Afra J. Zomorodian, Topology for Computing (Cambridge Monographs on Applied and Computational Mathematics), Cambridge University Press (September 28, 2009) google books preview
Additional readings (for Sept 4)
Persistent Brain Network Homology From the Perspective of Dendrogram, Hyekyoung Lee; Hyejin Kang; Chung, M.K.; Bung-Nyun Kim; Dong Soo Lee, Medical Imaging, IEEE Transactions on , vol.31, no.12, pp.2267,2277, Dec. 2012.
Week 3
Sept 9 video, pptx, pdf Create your own homology
Ghrist's A Sequence of Homologies video (pdf). From IMA New Directions Short Course Applied Algebraic Topology June 15-26, 2009
Sept 11 video, pptx, pdf Persistent homology
Topology and data, G Carlsson (2009)
H. Edelsbrunner, D. Letscher, and A. Zomorodian, Topological persistence and simpliction, Discrete and Computational Geometry 28, 2002, 511-533.
Ch 7 in Afra J. Zomorodian, Topology for Computing (Cambridge Monographs on Applied and Computational Mathematics), Cambridge University Press (September 28, 2009) google books preview
Sept 13 video, pptx, pdf Persistance homology (cont.)
Additional readings
Klein bottle
Topological analysis of population activity in visual cortex, Gurjeet Singh, Facundo Memoli, Tigran Ishkhanov, Guillermo Sapiro, Gunnar Carlsson, Dario L. Ringach, J Vis. 2008 Jun 30;8(8):11.1-18
Persistent Homology — a Survey. Herbert Edelsbrunner and John Harer, Contemporary Mathematics 453 (2008), 257 - 282

Week 4
Sept 16 video, pptx, pdf Persistent homology III
Javaplex,     Javaplex tutorial
Sept 18 video, pptx, pdf NKI data, Array5yr.csv
Sept 20 , pptx, pdf Persistent homology IV
Additional readings
Mathworks Matlab Tutorials
Kaggle data analysis competitions
Data for MATLAB hackers (pre-2010)
http://yann.lecun.com/exdb/mnist/
Using the MNIST Dataset
Week 5
Sept 23
Sept 25
Sept 27
Additional readings
Week 6
Sept 30
Oct 2-4
IMA pre-workshop (Oct 2-4): An Introduction to Statistics and Probability for Topologists
Additional readings
Week 7
Oct 7 - 11 IMA workshop: Topological Data Analysis
Week 8 Cohomology
Oct 14
Oct 16
Oct 18
Additional readings
Week 9 Cohomology
Oct 21
Oct 23
Oct 25
Additional readings
Week 10
Oct 28 - Nov 1 IMA workshop: Modern Applications of Homology and Cohomology
Week 11
Nov 4
Nov 6
Nov 8
Additional readings
Week 12
Nov 11
Nov 13
Nov 15
Additional readings
Week 13
Nov 18
Nov 20
Nov 22
Additional readings
Nov 25 - 29 Thanksgiving break
Week 14
Dec 2
Dec 4
Dec 6
Additional readings
Week 15
Dec 9-13 IMA workshop: Topological Structures in Computational Biology

Spring Activities: While the official course will end in December, we can continue online seminars/discussion meetings.


My tentative locations: I will be at the IMA (staying at the Wales house) October 1 - November 2 as well as December 2 - December 14. I will be at a conference Nov 17 - 22 and will likely visit a colleague before and/or after this conference (but the class is online, so we will still have regular class meetings). All other times, I will be at UI.

Recommended books/online notes:

Recommended textbooks (note these textbooks are NOT required as we will focus on published papers). Online notes/textbooks: Classic texts: